Spanning 106.5 miles along US Route 1 from Key West’s Mile Marker 0 to the Jewfish Creek Bridge on Key Largo, the Florida Keys Scenic Highway is one of America’s most iconic drives—and one of only 46 designated All-American Roads in the nation.

This extraordinary route hopscotches across 42 bridges connecting a chain of subtropical islands, with the turquoise waters of the Atlantic Ocean on one side and the calm Gulf of Mexico on the other. The legendary Seven Mile Bridge offers breathtaking open-water views that make you feel suspended between sea and sky.

Along the way, discover Key West’s colorful Victorian architecture and vibrant arts scene, snorkel at Bahia Honda State Park’s pristine beaches, explore the underwater wonders of John Pennekamp Coral Reef State Park, and spot tiny Key deer on Big Pine Key. Fresh seafood shacks, quirky roadside attractions, and laid-back island communities invite spontaneous stops.

Best time to visit: November through April offers ideal weather with less humidity and minimal hurricane risk.

Allow: At minimum 3-4 hours for a straight drive, but a full day or weekend lets you truly soak in the Keys’ unhurried island spirit. This is a journey meant to be savored, not rushed.

Explore Nearby

• Mitchell State Park — State Park in Michigan
• Big Cypress National Preserve — Dark Sky Site in Florida
• Fakahatchee Strand Preserve State Park — State Park in Florida
• Cape Florida Light — Lighthouse in Florida
• Fowey Rocks Light — Lighthouse in Florida